Vein disease is progressive which if left untreated is likely to become worse with time. Increasing symptoms that can occur with untreated varicose veins include leg tiredness, heaviness, aching, throbbing, restlessness, tingling, itching numbness and swelling. More serious complications such as phlebitis, blood clots, dermatitis, and vein ulcers can develop if varicose veins are left untreated.